This medication contains tolterodine. Do not take Detrol or Detrol LA if you are allergic to tolterodine or any ingredients contained in this drug. Accumulation of normeperidine as in chronic use or possibly following introduction of a concomitant CYP3A4 inducer presents as excitatory syndrome including hallucinations, tremors, muscle twitches, dilated pupils, hyperactive reflexes, and convulsions. If a CYP3A4 or CYP2B6 inhibitor is discontinued, consider increasing the Demerol Injection dosage until stable drug effects are achieved. Squeeze the muscles that you use stop the flow of urine. klatu.info neotrex
The following adverse reactions associated with the use of meperidine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. This means you have any two types of the condition. Many women have both stress and urge incontinence. It is unknown if this drug passes into milk. Consult your doctor before -feeding. If Demerol Injection is abruptly discontinued in a physically-dependent patient, a withdrawal syndrome may occur. Some or all of the following can characterize this syndrome: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, myalgia, and mydriasis. Other signs and symptoms also may develop, including: irritability, anxiety, backache, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, or increased blood pressure, respiratory rate, or heart rate.
Carbon dioxide CO 2 retention from opioid-induced respiratory depression can exacerbate the sedating effects of opioids. Pfizer also has programs that provide eligible patients with insurance support, copay assistance, and medicines for free. Assess each patient's risk for opioid addiction, abuse, or misuse prior to prescribing Demerol Injection, and monitor all patients receiving Demerol Injection for the development of these behaviors and conditions. Monitor patients for signs of urinary retention or reduced gastric motility when Demerol Injection is used concomitantly with anticholinergic drugs.
Monitor for signs of opioid withdrawal. Take this by as directed by your doctor, usually with food or milk. Follow your dosing instructions carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Different dosing schedules exist for this medication. If you are not taking the same dose each day or if you take this medication every other day, it may help to mark your calendar with a reminder. Consult your doctor or if you have any questions. PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Detrol LA extended-release capsules while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Detrol LA extended-release capsules.
You should not take this medication if you are allergic to tolterodine or fesoterodine Toviaz if you have untreated or uncontrolled narrow-angle glaucoma, or if you have a blockage of the urinary tract, stomach, or intestines. Avoid contact with people who have recently received live such as inhaled through the nose. MAO inhibitors those intended to treat psychiatric disorders and also others, such as linezolid and intravenous methylene blue. Do not increase your dose or take this medication more often than directed. Your condition will not improve any faster and your risk of serious side effects may be increased. Demerol Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia. Meperidine and normeperidine are excreted by kidneys. What should I avoid while taking tolterodine Detrol LA? Although the risk of addiction in any individual is unknown, it can occur in patients appropriately prescribed Demerol Injection. Addiction can occur at recommended dosages and if the drug is misused or abused.
The concomitant use of Demerol Injection and CYP3A4 or CYP2B6 inhibitors can increase the plasma concentration of meperidine, resulting in increased or prolonged opioid effects. Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs. Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of Demerol Injection in patients with impaired consciousness or coma. Studies in animals to evaluate the mutagenic potential of meperidine have not been conducted. Adults: The usual dosage is 50 mg to 150 mg intramuscularly or subcutaneously every 3 or 4 hours as needed for pain. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Concomitant use of Demerol Injection with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could decrease meperidine plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to meperidine. Talk to your doctor or about lifestyle changes that might benefit you. This list is not complete and there are many other drugs that can interact with tolterodine. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. It may be taken with or without food. The dosage is based on your medical condition and response to therapy. micronase
Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration. In patients with pheochromocytoma, meperidine has been reported to provoke hypertension. Do 3 or 4 sets daily. Demerol Injection may reduce respiratory drive, and the resultant CO 2 retention can further increase intracranial pressure. Monitor such patients for signs of sedation and respiratory depression, particularly when initiating therapy with Demerol Injection. Prescription drug abuse is the intentional non-therapeutic use of a prescription drug, even once, for its rewarding psychological or physiological effects. If you do not take the same dose each day or if you take this medication every other day, ask your doctor or what you should do if you miss a dose. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product. Drinking alcohol can increase some of the side effects of tolterodine. Other medications can affect the removal of from your body, which may affect how methylprednisolone works. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. The usual dosage is 50 mg to 100 mg intramuscularly or subcutaneously when pain becomes regular, and may be repeated at 1- to 3-hour intervals. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory. What other drugs will affect tolterodine Detrol? It is not known whether this drug passes into milk. Consult your doctor before -feeding. This program provides uninsured patients with savings on their prescriptions at the pharmacy. Ask your pharmacist about the safe use of those products.
If you are taking this once daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Meperidine causes miosis, even in total darkness. This medication is used to treat an overactive bladder. By relaxing the muscles in the bladder, tolterodine improves your ability to control your urination. It helps to reduce leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom. This medication belongs to the class of drugs known as antispasmodics. In an individual physically dependent on opioids, administration of the recommended usual dosage of the antagonist will precipitate an acute withdrawal syndrome. The severity of the withdrawal symptoms experienced will depend on the degree of physical dependence and the dose of the antagonist administered. If a decision is made to treat serious respiratory depression in the physically dependent patient, administration of the antagonist should be begun with care and by titration with smaller than usual doses of the antagonist. Americans, most of them women. There are several different types, causes, and treatments. Ureteroscopy: This procedure treats stones in the kidneys and ureters. Your doctor uses a thin, flexible scope to find and remove stones. To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand. Demerol Injection is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. What is tolterodine Detrol LA? Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. Respiratory depression, if not immediately recognized and treated, may lead to respiratory arrest and death. With this type, urine leaks due to weakened pelvic floor muscles and tissues. discount ibuprofen tablets
Demerol Injection contains meperidine, a Schedule II controlled substance. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. The safety and effectiveness of meperidine in pediatric patients has not been established. Literature reports indicate that meperidine has a slower elimination rate in neonates and young infants compared to older children and adults. Neonates and young infants may also be more susceptible to the effects, especially the respiratory depressant effects. If meperidine use is contemplated in neonates or young infants, any potential benefits of the drug need to be weighed against the relative risk of the patient. Meperidine produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation see above drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. This may interfere with certain laboratory tests such as possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; chest pain; confusion, disorientation, or memory problems; difficult or painful urination; fast or irregular heartbeat; fainting; hallucinations; severe dizziness; swelling of the hands, ankles, or feet. Your doctor may occasionally change your dose to make sure you get the best results. This medication may lower your ability to fight infections. This may make you more likely to get a serious rarely fatal infection or make any infection you have worse. Gastrointestinal. Dry mouth, constipation, biliary tract spasm. MD, assistant professor of medicine, director, IBD Center, Georgetown University Hospital, Washington DC; expert, Crohn's amp; Colitis Foundation of America.
Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. Parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. Pfizer also has programs that provide eligible patients with insurance, support assistance, and medicines at a savings. Contact Pfizer RxPathways for details 844-989-7284. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Serious, life-threatening, or fatal respiratory depression may occur with use of Demerol Injection. Flecainide can affect your heart's rhythm. Other drugs can have the same effect. Prolonged use of Demerol Injection during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. DEMEROL is not a trademark of Hospira. Meperidine is contraindicated in patients who are receiving monoamine oxidase MAO inhibitors or those who have recently received such agents. Therapeutic doses of meperidine have occasionally precipitated unpredictable, severe, and occasionally fatal reactions in patients who have received such agents within 14 days. The mechanism of these reactions is unclear, but may be related to a preexisting hyperphenylalaninemia. Some have been characterized by coma, severe respiratory depression, cyanosis, and hypotension, and have resembled the syndrome of acute narcotic overdose. Serotonin syndrome with agitation, hyperthermia, diarrhea, tachycardia, sweating, tremors and impaired consciousness may also occur. In other reactions the predominant manifestations have been hyperexcitability, convulsions, tachycardia, hyperpyrexia, and hypertension. Tolterodine reduces spasms of the bladder muscles. If concomitant use is necessary, consider dosage reduction of Demerol Injection until stable drug effects are achieved. Monitor patients for respiratory depression and sedation at frequent intervals. All patients treated with opioids require careful monitoring for signs of abuse and addiction, since use of opioid analgesic products carries the risk of addiction even under appropriate medical use. Do not stop taking this medication without consulting your doctor. Meperidine should therefore be used with caution in patients with renal impairment. Titrate the dosage of Demerol Injection slowly in patients with renal impairment and monitor closely for signs of central nervous system and respiratory depression. Some medical conditions may interact with Detrol LA extended-release capsules. buy lamivudine malta
The treatment takes about an hour, and you can usually go home about an hour later. Oxybutynin belongs to a class of drugs known as antispasmodics. Do not share this medication with others. Drug-seeking" behavior is very common in persons with substance use disorders. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing, or referral, repeated "loss" of prescriptions, tampering with prescriptions, and reluctance to provide prior medical records or contact information for other treating health care providers. "Doctor shopping" visiting multiple prescribers to obtain additional prescriptions is common among drug abusers and people suffering from untreated addiction. Preoccupation with achieving adequate pain relief can be appropriate behavior in a patient with poor pain control. If concomitant use is necessary, consider increasing the Demerol Injection dosage until stable drug effects are achieved. Monitor for signs of opioid withdrawal. If a CYP3A4 or CYP2B6 inducer is discontinued, consider Demerol Injection dosage reduction and monitor for signs of respiratory depression. Drowsiness and confusion can increase the risk of falling. To relieve dry mouth, suck sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Other. Pain at injection site; local tissue irritation and induration following subcutaneous injection, particularly when repeated; antidiuretic effect. Detrol LA extended-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people. Because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate.
The dose of Demerol Injection should be proportionately reduced usually by 25 to 50 percent when administered concomitantly with phenothiazines and many other tranquilizers since they potentiate the action of Demerol Injection. If any of these effects persists or worsens, tell your doctor or promptly. But they are created when your has high levels of certain minerals. Injections and surgery. Shots to bulk up your urethral area may help. In more extreme cases, you may need surgery. One procedure pulls the bladder back up to a more normal position, relieving the pressure and leakage. The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tolterodine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems heart failure, slow heartbeat, QT prolongation in the EKG family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. The concomitant use of acyclovir may increase the plasma concentrations of meperidine and its metabolite, normeperidine. Inform your doctor if your condition persists or worsens. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Most people with not feel sick. Read the Patient Information Leaflet if available from your pharmacist before you start using tolterodine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately. Take this medication by mouth with or without food as directed by your doctor, usually once a day. Swallow the medication whole with a full glass of liquid. Do not crush or chew the medication. Doing so can destroy the long action of the drug and may increase side effects. rabeprazole
What happens if I overdose Detrol? Before you take tolterodine, tell your doctor if you have kidney or liver disease, glaucoma, myasthenia gravis, or a personal or family history of "Long QT syndrome. Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, Philippides GJ, Roden DM, Zareba W. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Side Effects List Detrol LA side effects by likelihood and severity. Demerol Injection should not be used for treatment of chronic pain. If the level of pain increases after dosage stabilization, attempt to identify the source of increased pain before increasing the Demerol Injection dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between management of pain and opioid-related adverse reactions. All medicines may cause side effects, but many people have no, or minor, side effects. Your condition will not improve any faster, and your risk of side effects will increase. Ask your health care provider any questions you may have about how to use Detrol LA extended-release capsules. This information should not be used to decide whether or not to take Detrol LA extended-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Detrol LA extended-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Detrol LA extended-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Detrol LA extended-release capsules. What should I discuss with my healthcare provider before taking tolterodine Detrol? How should I take tolterodine Detrol LA? This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages. Take this by with or without food as directed by your doctor, usually once or twice daily. What should I avoid while taking tolterodine Detrol?
This may not be a complete list of all interactions that may occur. Ask your health care provider if Detrol LA extended-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Studies to determine the effect of meperidine on fertility have not been conducted. This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. Due to additive pharmacologic effect, the concomitant use of benzodiazepines or other CNS depressants, including alcohol, can increase the risk of hypotension respiratory depression, profound sedation, coma, and death. Concomitant use of Demerol Injection with monoamine oxidase MAO inhibitors can result in coma, severe respiratory depression, cyanosis, and hypotension. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. What are the possible side effects of tolterodine Detrol? Because the duration of opioid reversal is expected to be less than the duration of action of meperidine in Demerol Injection, carefully monitor the patient until spontaneous respiration is reliably re-established. If the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed by the product's prescribing information. discount nolpaza zamienniki
Discuss the risks and benefits with your doctor. Methylprednisolone may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Instructions for using the Carpuject Syringe are available with the reusable Carpuject Holder. Carpuject Single-use cartridges are to be used ONLY with Carpuject Holders. If your symptoms do not improve or if they become worse, check with your doctor. Tolterodine may also be used for purposes not listed in this medication guide.
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It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding. The meperidine in Demerol Injection may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis, for worsening symptoms. Monitor these patients for signs of hypotension after initiating or titrating the dosage of Demerol Injection. In patients with circulatory shock, Demerol Injection may cause vasodilation that can further reduce cardiac output and blood pressure. Avoid the use of Demerol Injection in patients with circulatory shock.
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. See "What Are Side Effects Associated with Using Tolterodine? If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Discontinue Demerol Injection if serotonin syndrome is suspected. Read the Patient Information Leaflet if available from your before you start taking and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication may cause to not work as well. Live may cause serious problems such as infection if given while you are using this medication. Do NOT change your dose of Detrol LA extended-release capsules without checking with your doctor. This is a long-acting form of that is used to treat and urinary conditions.
The stones can be brown or yellow, and smooth or rough. Meperidine appears in the milk of nursing mothers receiving the drug. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Demerol Injection and any potential adverse effects on the breastfed infant from Demerol Injection or from the underlying maternal condition. Follow patients for signs and symptoms of respiratory depression and sedation.